Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | LIPE | Q05469 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120724 | 0.95 | PPARG (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4SCN9A | |
| SCHEMBL5107803 | 0.90 | SCN9A (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4SCN9A | |
| SCHEMBL5107293 | 0.90 | PPARG (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4SCN9A | |
| SCHEMBL5119989 | 0.85 | PPARG (0.56) | PPARGLIPESMN1; SMN2 | |
| SCHEMBL5119630 | 0.85 | PSEN1 (0.40) | PPARGPPARDPPARA | |
| SCHEMBL5119821 | 0.85 | PPARG (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4SCN9A | |
| SCHEMBL5120546 | 0.83 | PPARG (0.55) | PPARGLIPESMN1; SMN2 | |
| SCHEMBL5113266 | 0.80 | SCN9A (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4SCN9A | |
| SCHEMBL6035849 | 0.78 | MLYCD (0.36) | PPARGPPARDPPARA | |
| SCHEMBL5115463 | 0.78 | PPARG (0.46) | PPARGLIPEPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | PLAAT3 4016/4885PLAAT5 4316/4885PLAAT2 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.