Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118895 | 0.85 | MCOLN3 (0.51) | BDKRB1ALDH1A1L3MBTL1MCOLN3KMT2A | |
| SCHEMBL5115163 | 0.84 | HTT (0.44) | BDKRB1ALDH1A1L3MBTL1MCOLN3 | |
| SCHEMBL5118257 | 0.76 | BDKRB1 (0.57) | BDKRB1ALDH1A1L3MBTL1MCOLN3POLB | |
| SCHEMBL4032633 | 0.75 | HTT (0.48) | NR1H4BDKRB1DAGLAALDH1A1L3MBTL1 | |
| SCHEMBL5125648 | 0.74 | KEAP1 (0.49) | C1RPRSS1ALDH1A1 | |
| SCHEMBL5125650 | 0.74 | KEAP1 (0.49) | C1RPRSS1ALDH1A1 | |
| SCHEMBL4033897 | 0.72 | GSTO1 (0.46) | NR1H4BDKRB1DAGLAC1RPRSS1 | |
| SCHEMBL5124229 | 0.71 | GAA (0.48) | NR1H4BDKRB1DAGLAALDH1A1L3MBTL1 | |
| SCHEMBL5115358 | 0.70 | RAB9A (0.56) | BDKRB1ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL5115360 | 0.70 | RAB9A (0.56) | BDKRB1ALDH1A1L3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | UGT1A1, UGT2B7, UGT1A6 | NR1H4 15/4885BDKRB1 1217/4885DAGLA 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.