Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984418 | 0.87 | HSD17B10 (0.39) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL2523959 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1806779 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1806781 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL27816835 | 0.84 | S1PR3 (0.43) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL18745553 | 0.83 | POLB (0.42) | ALDH1A1LMNATSHRHPGDSFRP1 | |
| SCHEMBL6429457 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL10577881 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL20854288 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1804271 | 0.82 | TIMP3 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11376272-B2 | Methods of modulating immune activity | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| US-11180657-B2 | Polysulfonated fluorescence dyes | ATTO-TEC GMBH (DE) | 2021-11-23 | — | — | US | disclosed |
| US-20210299155-A1 | METHODS OF MODULATING IMMUNE ACTIVITY | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-30 | — | — | US | disclosed |
| EP-3461815-B1 | NOVEL POLY SULFONATED FLUORESCENCE DYES | ATTO TEC GMBH (DE) | 2021-03-03 | — | — | EP | disclosed |
| US-20190322870-A2 | NOVEL POLYSULFONATED FLUORESCENCE DYES | ATTO-TEC GMBH (DE) | 2019-10-24 | — | — | US | disclosed |
| US-20190100653-A1 | NOVEL POLYSULFONATED FLUORESCENCE DYES | ATTO-TEC GMBH (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-3461815-A1 | NOVEL POLY SULFONATED FLUORESCENCE DYES | ATTO-TEC GmbH (DE) | 2019-04-03 | — | — | EP | disclosed |
| US-8647880-B2 | Mass spectrometry-based protein identification method with selective N-terminus derivatization | Rudjer Bosckovic Institute (HR) | 2014-02-11 | — | — | US | disclosed |
| US-20110212531-A1 | Mass Spectrometry-Based Protein Identification Method | RUDJER BOSKOVIC INSTITUTE (HR) | 2011-09-01 | — | — | US | disclosed |
| US-7456321-B2 | Process for producing high-purity 4,4′-dihydroxydiphenyl sulfone | KONISHI CHEMICAL IND. CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| CN-1314664-C | Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone | KONISHI CHEM IND (JP) | 2007-05-09 | — | — | CN | disclosed |
| US-20050272956-A1 | Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone | KONISHI CHEMICAL IND. CO., LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| CN-1684943-A | Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone | KONISHI CHEM IND (JP) | 2005-10-19 | — | — | CN | disclosed |
| EP-0443046-B1 | PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE | KONISHI CHEM IND (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5189223-A | PROCESS FOR PREPARATION OF 4,4'-DIHYDROXYDIPHENYLSULFONE | KONISHI CHEMICAL IND. CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0443046-A1 | PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE | KONISHI CHEMICAL IND. CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11376272-B2 | Methods of modulating immune activity | STING1, IRF3, CGAS | ALDH1A1 4487/4885HSD17B10 4810/4885CASP6 1992/4885 |
| US-11180657-B2 | Polysulfonated fluorescence dyes | CD44, ARSA, STS | ALDH1A1 199/4885HSD17B10 2302/4885CASP6 1929/4885 |
| US-20210299155-A1 | METHODS OF MODULATING IMMUNE ACTIVITY | STING1, IRF3, CGAS | ALDH1A1 4549/4885HSD17B10 4832/4885CASP6 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.