Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 7/20 | 0.37 |
| ▸ | MMP13 | P45452 | 6/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.37 |
| ▸ | MMP2 | P08253 | 6/20 | 0.37 |
| ▸ | MMP14 | P50281 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348533 | 0.90 | ADAMTS4 (0.38) | NPC1RAB9AADAMTS4MMP13MMP2 | |
| SCHEMBL963562 | 0.86 | NPC1 (0.42) | NPC1RAB9ACNR2CNR1ADAMTS4 | |
| SCHEMBL2484519 | 0.82 | DRD4 (0.40) | NPC1RAB9ACNR2CNR1ADAMTS4 | |
| SCHEMBL16715300 | 0.81 | LMNA (0.33) | LMNAALDH1A1CHRM1DRD4EPHX2 | |
| SCHEMBL3516007 | 0.80 | ADAMTS4 (0.42) | CNR2CNR1ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL30823619 | 0.78 | GAA (0.41) | LMNAALDH1A1 | |
| SCHEMBL1180196 | 0.78 | GAA (0.41) | LMNAALDH1A1 | |
| SCHEMBL28886134 | 0.77 | DRD2 (0.42) | CHRM2CHRM1KCNH2DRD4HTR2A | |
| SCHEMBL17797569 | 0.75 | LMNA (0.34) | NPC1RAB9ACNR2CNR1LMNA | |
| SCHEMBL816601 | 0.75 | GAA (0.39) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBVIE INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058335-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, OPRL1 | NPC1 486/4885RAB9A 1315/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.