Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.67 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411328 | 0.86 | MIF (0.53) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL23651250 | 0.85 | MIF (0.49) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL23636527 | 0.85 | MAOA (0.51) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL103400 | 0.84 | MIF (0.72) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL20414716 | 0.84 | ALDH1A1 (0.69) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL28428943 | 0.83 | KDM4E (0.71) | MIFMEN1KMT2AKDM4EMAPT | |
| SCHEMBL24803038 | 0.83 | SLC16A3 (0.67) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL2082378 | 0.81 | FLT3 (0.61) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL1406240 | 0.81 | MIF (1.00) | MIFPFKFB3MEN1KMT2AKDM4E | |
| SCHEMBL14134576 | 0.81 | KDM4E (0.71) | MIFPFKFB3MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | disclosed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SLC5A2, CYP2D6, IAPP | MIF 2485/4885PFKFB3 880/4885MEN1 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.