SCHEMBL5116598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5129498	0.90	GAA (0.42)	MAPTKMT2AALDH1A1MEN1TRPA1
	SCHEMBL5122888	0.86	ADRA1B (0.52)	MAPTKMT2AALDH1A1TOP2AGAA
	SCHEMBL5118720	0.86	PKLR (0.55)	MAPTKMT2AALDH1A1MEN1GAA
	SCHEMBL5117981	0.83	MAPT (0.61)	MAPTKMT2AALDH1A1MEN1TRPA1
	SCHEMBL5113864	0.82	GAA (0.49)	MAPTKMT2AALDH1A1MEN1GAA
	SCHEMBL5118714	0.82	ALOX5 (0.49)	MAPTALDH1A1TRPA1GAABACE1
	SCHEMBL5114962	0.81	BRD4 (0.48)	MAPTKMT2AALDH1A1GAABRD4
	SCHEMBL5114996	0.80	MAPT (0.48)	MAPTKMT2AALDH1A1MEN1TRPA1
	SCHEMBL5114433	0.79	NR1H4 (0.38)	MAPTKMT2AALDH1A1TRPA1TOP2A
	SCHEMBL1252706	0.78	IDO1 (0.54)	MAPTALDH1A1GAABRD4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.