Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 20/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278774 | 0.87 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL5117436 | 0.86 | TAS2R14 (0.74) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1279410 | 0.79 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1287359 | 0.79 | TAS2R14 (0.83) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1170228 | 0.78 | TAS2R14 (0.78) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1614985 | 0.77 | TAS2R14 (0.80) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL12863433 | 0.77 | TAS2R14 (0.79) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1278788 | 0.77 | TAS2R14 (0.97) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL4913460 | 0.77 | TAS2R14 (0.80) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1278616 | 0.76 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345095-B2 | Sulfonamide compounds for the treatment of neurodegenerative disorders | PFIZER INC (US) | 2008-03-18 | — | — | US | disclosed |