Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 19/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116615 | 0.86 | TAS2R14 (0.76) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1279183 | 0.86 | TAS2R14 (1.00) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL15114844 | 0.83 | TAS2R14 (0.95) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1279439 | 0.80 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL1278788 | 0.79 | TAS2R14 (0.97) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL5116370 | 0.79 | CXCR3 (0.56) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1279325 | 0.79 | TAS2R14 (1.00) | TAS2R14MEN1KMT2APOLB | |
| SCHEMBL1278616 | 0.78 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL5115952 | 0.78 | TAS2R14 (0.60) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1615743 | 0.77 | TAS2R14 (0.90) | TAS2R14CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345095-B2 | Sulfonamide compounds for the treatment of neurodegenerative disorders | PFIZER INC (US) | 2008-03-18 | — | — | US | disclosed |