Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872903 | 0.86 | NPC1 (0.54) | KDM4ELMNAALDH1A1DHODHNPC1 | |
| SCHEMBL16568961 | 0.86 | NPC1 (0.54) | KDM4ELMNAALDH1A1DHODHNPC1 | |
| SCHEMBL29226750 | 0.84 | ILK (0.59) | SMN1; SMN2KDM4ELMNANFKB1NFKB2 | |
| SCHEMBL5755756 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2KDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL17859467 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EALDH1A1DHODHNPC1 | |
| SCHEMBL5118299 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2KDM4ELMNAALDH1A1DHODH | |
| SCHEMBL687318 | 0.77 | ALDH1A1 (0.46) | LMNAALDH1A1DHODHNPC1RAB9A | |
| SCHEMBL20969720 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2KDM4ELMNAALDH1A1DHODH | |
| SCHEMBL8975728 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2KDM4ELMNAALDH1A1DHODH | |
| SCHEMBL30537926 | 0.75 | PARP1 (0.47) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164924-A | Amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-2959918-B1 | ANTI-MALIGNANT TUMOR AGENT COMPOSITION | J PHARMA CO LTD (JP) | 2019-05-22 | — | — | EP | disclosed |
| US-10172835-B2 | Anticancer agent composition | J-PHARMA CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20160279103-A1 | AN ANTICANCER AGENT COMPOSITION | J-PHARMA CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |
| CN-105392498-A | Anti-malignant tumor agent composition | PHARMA CO LTD J | 2016-03-09 | — | — | CN | disclosed |
| EP-2959918-A1 | ANTI-MALIGNANT TUMOR AGENT COMPOSITION | J-Pharma Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-1481965-B1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | ENDO HITOSHI (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-7345068-B2 | Aromatic amino acid derivatives and medicinal compositions | Endou, Hitoshi (JP) | 2008-03-18 | — | — | US | disclosed |
| CN-1293042-C | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1630632-A | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | HITOSHI ENDOU (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1481965-A1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | Endo, Hitoshi (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160279103-A1 | AN ANTICANCER AGENT COMPOSITION | TUBB1, TUBA1A, TUBA1C | SMN1; SMN2 1404/4885KDM4E 4145/4885LMNA 2092/4885 |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | SLC7A1, SLC1A5, SLC7A5 | SMN1; SMN2 4118/4885KDM4E 1714/4885LMNA 3373/4885 |
| US-10172835-B2 | Anticancer agent composition | TOP1, TUBB1, TUBA1A | SMN1; SMN2 1763/4885KDM4E 4258/4885LMNA 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.