Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 5/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116955 | 1.00 | PARP10 (0.50) | PARP10PARP11HPGDL3MBTL1HRH3 | |
| SCHEMBL9488600 | 0.85 | HPGD (0.57) | PARP10PARP11HPGDL3MBTL1HRH3 | |
| SCHEMBL22043642 | 0.83 | L3MBTL1 (0.53) | HPGDL3MBTL1HTTALDH1A1LMNA | |
| SCHEMBL31552701 | 0.83 | L3MBTL1 (0.53) | HPGDL3MBTL1HTTALDH1A1LMNA | |
| SCHEMBL5123716 | 0.83 | HTT (0.56) | PARP10PARP11HPGDL3MBTL1ESR2 | |
| SCHEMBL5123714 | 0.83 | PARP10 (0.50) | PARP10PARP11HPGDL3MBTL1HTT | |
| SCHEMBL5123710 | 0.83 | PARP10 (0.50) | PARP10PARP11HPGDL3MBTL1HTT | |
| SCHEMBL5123713 | 0.83 | HTT (0.56) | PARP10PARP11HPGDL3MBTL1ESR2 | |
| SCHEMBL5117027 | 0.82 | HTT (0.47) | HPGDL3MBTL1HRH3HTTHSD17B1 | |
| SCHEMBL5117032 | 0.82 | HTT (0.47) | HPGDL3MBTL1HRH3HTTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414142-B2 | 5-aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators | WYETH (US) | 2008-08-19 | — | — | US | disclosed |
| US-20070066637-A1 | 5-Aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators | WYETH (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066637-A1 | 5-Aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators | CYP19A1, PGR, GNRHR | PARP10 1100/4885PARP11 1327/4885HPGD 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.