Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5112961 | 0.87 | NR1I2 (0.42) | ALDH1A1MAPK1NR1I2SMN1; SMN2GSTO1 | |
| SCHEMBL5127766 | 0.81 | CA12 (0.39) | ALDH1A1MAPK1NR1I2SMN1; SMN2GSTO1 | |
| SCHEMBL5128143 | 0.75 | NR1I2 (0.44) | ALDH1A1MAPK1NR1I2SMN1; SMN2GSTO1 | |
| SCHEMBL5124458 | 0.74 | GRM6 (0.39) | ALDH1A1MAPK1NR1I2SMN1; SMN2TSHR | |
| SCHEMBL5123264 | 0.70 | CA12 (0.39) | ALDH1A1MAPK1NR1I2SMN1; SMN2GSTO1 | |
| SCHEMBL5122274 | 0.70 | NPC1 (0.42) | ALDH1A1MAPK1SMN1; SMN2GSTO1TSHR | |
| SCHEMBL5123269 | 0.70 | PTPN1 (0.43) | TSHRPTPN1 | |
| SCHEMBL5123712 | 0.70 | CA12 (0.39) | ALDH1A1MAPK1NR1I2SMN1; SMN2GSTO1 | |
| SCHEMBL6674123 | 0.68 | ALDH1A1 (0.58) | ALDH1A1MAPK1SMN1; SMN2TSHRPKM | |
| SCHEMBL1731122 | 0.67 | KEAP1 (0.41) | ALDH1A1NR1I2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | WYETH (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004325-A1 | PTP1B inhibitors | PTPA, PTPRJ, PTPRR | ALDH1A1 1266/4885MAPK1 587/4885NR1I2 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.