SCHEMBL5117078

SCHEMBL5117078

NC(=O)c1ccccc1-c1ccccc1-c1cc[nH]n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.51
CSNK1A1 P48729 1/20 0.49
TYRO3 Q06418 1/20 0.49
DYRK1B Q9Y463 1/20 0.49
NUDT1 P36639 1/20 0.47
METAP2 P50579 1/20 0.41
CHEK1 O14757 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GRM5 P41594 1/20 0.39
CTNNB1 P35222 1/20 0.37
PARP1 P09874 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696661 0.93 BCAT2 (0.55) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL30528244 0.93 BCAT2 (0.55) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL30528245 0.93 BCAT2 (0.55) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL3423724 0.83 BCAT2 (0.42) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL3418979 0.81 BCAT2 (0.41) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL7159727 0.81 BCAT2 (0.41) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL7159631 0.81 BCAT2 (0.41) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL8070725 0.81 CSNK1A1 (0.49) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL21874742 0.80 BCAT2 (0.36) BCAT2CSNK1A1TYRO3DYRK1BNUDT1
SCHEMBL3421536 0.79 BCAT2 (0.39) BCAT2CSNK1A1TYRO3DYRK1BNUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348350-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms BAYER CROPSCIENCE AG (DE) 2008-03-25 US claimed
US-6992098-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2006-01-31 US claimed
CN-1222514-C Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER AG (DE) 2005-10-12 CN claimed
US-20050182120-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms ELBE HANS-LUDWIG (DE) 2005-08-18 US claimed
JP-2004523467-A 2004-08-05 JP claimed
US-20040053971-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2004-03-18 US claimed
CN-1466578-A Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-01-07 CN claimed
EP-1313709-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES Bayer CropScience AG (DE) 2003-05-28 EP claimed
WO-2002008195-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2002-01-31 WO claimed
US-7348350-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms BAYER CROPSCIENCE AG (DE) 2008-03-25 US disclosed
US-7348350-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms BAYER CROPSCIENCE AG (DE) 2008-03-25 US disclosed
US-6992098-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2006-01-31 US disclosed
US-6992098-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2006-01-31 US disclosed
US-20050182120-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms ELBE HANS-LUDWIG (DE) 2005-08-18 US disclosed
US-20040053971-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2004-03-18 US disclosed
EP-1313709-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES Bayer CropScience AG (DE) 2003-05-28 EP disclosed
EP-1313709-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES Bayer CropScience AG (DE) 2003-05-28 EP disclosed
WO-2002008195-A8 PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS BAYER AG (DE) 2002-04-04 WO disclosed
WO-2002008195-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2002-01-31 WO disclosed
WO-2002008195-A1 PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053971-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms MRPL21, Q6ZSR9, MRM1 BCAT2 461/4885CSNK1A1 1738/4885TYRO3 2931/4885
US-20050182120-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms DDT, MRPL21, DCXR BCAT2 638/4885CSNK1A1 2691/4885TYRO3 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.