Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514019 | 0.80 | BRD4 (0.38) | HSD17B10LMNAHPGDHIF1AALDH1A1 | |
| SCHEMBL11152677 | 0.77 | NT5E (0.41) | ING2HSD17B10LMNAHPGDHIF1A | |
| SCHEMBL2863381 | 0.77 | HSD17B10 (0.36) | HSD17B10LMNAHPGDHIF1AALDH1A1 | |
| SCHEMBL9793017 | 0.77 | CASR (0.38) | LCKFYNING2LMNAALDH1A1 | |
| SCHEMBL1808723 | 0.76 | LCK (0.34) | LCKFYNING2HSD17B10LMNA | |
| SCHEMBL1808721 | 0.76 | LCK (0.34) | LCKFYNING2HSD17B10LMNA | |
| SCHEMBL11152673 | 0.75 | PRMT1 (0.54) | HSD17B10HIF1AALDH1A1CASP6CYP2C9 | |
| SCHEMBL5115210 | 0.75 | ALDH1A1 (0.41) | HSD17B10LMNAHPGDHIF1AALDH1A1 | |
| SCHEMBL9792854 | 0.75 | CASR (0.37) | LCKFYNING2LMNAALDH1A1 | |
| SCHEMBL1802913 | 0.75 | ALDH1A1 (0.34) | LCKFYNING2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456321-B2 | Process for producing high-purity 4,4′-dihydroxydiphenyl sulfone | KONISHI CHEMICAL IND. CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20050272956-A1 | Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone | KONISHI CHEMICAL IND. CO., LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| EP-0443046-B1 | PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE | KONISHI CHEM IND (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5189223-A | PROCESS FOR PREPARATION OF 4,4'-DIHYDROXYDIPHENYLSULFONE | KONISHI CHEMICAL IND. CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0443046-A1 | PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE | KONISHI CHEMICAL IND. CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |