SCHEMBL5117735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5722769	0.91	THRA (0.49)	THRATHRBRHOCRHOAMRGPRX4
	SCHEMBL5106633	0.90	RHOC (0.43)	THRATHRBRHOCRHOAMEN1
	SCHEMBL4934248	0.90	THRA (0.44)	THRATHRBRHOCRHOAMEN1
	SCHEMBL5104851	0.90	RHOC (0.42)	RHOCRHOAHTTL3MBTL1MRGPRX4
	SCHEMBL4924564	0.90	THRA (0.45)	THRATHRBRHOCRHOAMEN1
	SCHEMBL5111593	0.89	THRA (0.42)	THRATHRBRHOCRHOAMEN1
	SCHEMBL4346172	0.88	THRA (0.47)	THRATHRBRHOCRHOAMEN1
	SCHEMBL5116634	0.87	BRD4 (0.39)	THRATHRBMEN1KMT2ASMN1; SMN2
	SCHEMBL5109507	0.86	THRA (0.42)	THRATHRBRHOCRHOAMEN1
	SCHEMBL5722548	0.86	PPARD (0.39)	THRATHRBRHOCRHOAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.