SCHEMBL51186

SCHEMBL51186

CCCCC1OC1CCCC

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.35
SPHK1 Q9NYA1 4/20 0.34
SPHK2 Q9NRA0 3/20 0.34
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9133300 1.00 TSHR (0.38) TSHRLMNACYP1A2ALDH1A1THRB
SCHEMBL7110791 1.00 TSHR (0.38) TSHRLMNACYP1A2ALDH1A1THRB
SCHEMBL51199 0.94 CYP1A2 (0.35) TSHRLMNACYP1A2ALDH1A1THRB
SCHEMBL51023 0.94 ALDH1A1 (0.44) TSHRCYP1A2ALDH1A1THRBSPHK1
SCHEMBL9801856 0.91 ALDH1A1 (0.48) TSHRCYP1A2ALDH1A1THRBSPHK1
SCHEMBL8497770 0.91 ALDH1A1 (0.48) TSHRCYP1A2ALDH1A1THRBSPHK1
SCHEMBL17787240 0.91
SCHEMBL9801842 0.91 ALDH1A1 (0.48) TSHRCYP1A2ALDH1A1THRBSPHK1
SCHEMBL9806300 0.91 ALDH1A1 (0.48) TSHRCYP1A2ALDH1A1THRBSPHK1
SCHEMBL9806346 0.91 ALDH1A1 (0.48) TSHRCYP1A2ALDH1A1THRBSPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535707-B Pneumatic tire 横滨橡胶株式会社 2021-05-25 CN disclosed
EP-2508342-B1 INNER LINER FOR PNEUMATIC TIRE, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-04-01 EP disclosed
EP-2508343-B1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-03-11 EP disclosed
EP-2554372-B1 MULTILAYERED STRUCTURE AND LAMINATE AND METHOD FOR PRODUCTION OF THE SAME KURARAY CO (JP) 2020-01-08 EP disclosed
US-10323143-B2 Polyvinyl acetal composition KURARAY CO., LTD. (JP) 2019-06-18 US disclosed
EP-2857451-B1 PNEUMATIC TIRE YOKOHAMA RUBBER CO LTD (JP) 2019-05-08 EP disclosed
CN-107116869-B Multilayer structure making, pneumatic tire inner liner and pneumatic tire 株式会社普利司通 2019-04-30 CN disclosed
EP-2623315-B1 MULTILAYERED STRUCTURE, INNER LINER HAVING THE SAME, AND PNEUMATIC TIRE KURARAY CO (JP) 2019-04-17 EP disclosed
EP-2716445-B1 MULTI-LAYERED STRUCTURE, INNER LINER FOR PNEUMATIC TIRE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2019-04-10 EP disclosed
US-10202620-B2 Synthesis of olefinic alcohols via enzymatic terminal hydroxylation PROVIVI, INC. (US) 2019-02-12 US disclosed
US-6348608-B1 ADDING OXIDIZING AGENT TO REACTION SOLUTION COMPRISING CHIRAL CYCLIC ENANTIOMERICALLY ENRICHED KETONE AND OLEFIN UNDER CONDITIONS EFFECTIVE TO GENERATE ENANTIOMERICALLY ENRICHED EPOXIDE, SEPARATING EPOXIDE FROM REACTION SOLUTION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2002-02-19 US disclosed
EP-1021426-A1 CATALYTIC ASYMMETRIC EPOXIDATION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-07-26 EP disclosed
EP-1021426-A4 CATALYTIC ASYMMETRIC EPOXIDATION UNIV COLORADO STATE RES FOUND (US) 2000-07-26 EP disclosed
WO-1998015544-A1 CATALYTIC ASYMMETRIC EPOXIDATION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1998-04-16 WO disclosed
US-5736174-A Alkoxylated alcohol fat substitutes ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-04-07 US disclosed
US-5466838-A Catalytic reaction of olefin with oxygen in the presence of aldehyde SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0540009-B1 Process for producing epoxides SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
US-5367087-A Process for producing epoxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
US-4360698-A FROM ALIPHATIC ALCOHOLS AND OXIRANE COMPOUND THE DOW CHEMICAL COMPANY (US) 1982-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202620-B2 Synthesis of olefinic alcohols via enzymatic terminal hydroxylation CYP2E1, ADH5, CYP1A2 TSHR 2674/4885LMNA 3013/4885CYP1A2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.