Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110649 | 0.88 | MRGPRX4 (0.50) | MRGPRX4ENPP2SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL5105315 | 0.84 | MRGPRX4 (0.64) | MRGPRX4ENPP2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5114936 | 0.81 | MRGPRX4 (0.71) | MRGPRX4SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL22480615 | 0.76 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL31568468 | 0.76 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL5120342 | 0.76 | FFAR4 (0.48) | MRGPRX4SMN1; SMN2FFAR4 | |
| SCHEMBL11509340 | 0.75 | MRGPRX4 (0.54) | MRGPRX4SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL5107914 | 0.75 | GRIN2D (0.55) | CYP1A2GAACYP2D6CYP2C19FFAR4 | |
| SCHEMBL5106677 | 0.74 | PPARG (0.51) | MRGPRX4RAB9AHPGDFFAR4USP2 | |
| SCHEMBL16687444 | 0.71 | ENPP2 (0.85) | MRGPRX4ENPP2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | MRGPRX4 826/4885ENPP2 2257/4885SMN1; SMN2 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.