SCHEMBL512003

SCHEMBL512003

CC(=O)N[Si](C)(C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CA2 P00918 1/20 0.33
PTGS1 P23219 1/20 0.33
MMP12 P39900 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7757364 0.80
SCHEMBL24436902 0.74 KDM4E (0.35) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL450522 0.69 KDM4E (0.41) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL321022 0.69
SCHEMBL451023 0.69 KDM4E (0.41) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL27617828 0.67
SCHEMBL2987964 0.65 KDM4E (0.44) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL26965406 0.65 KDM4E (0.44) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL9721813 0.63 KDM4E (0.35) KDM4ECA2PTGS1MMP12ALDH1A1
SCHEMBL11549452 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883932-B2 Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK DEGUSSA GMBH (DE) 2014-11-11 US claimed
US-20120029090-A1 Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK GOLDSCHMIDT GMBH (DE) 2012-02-02 US claimed
US-9334354-B2 Modified alkoxylation products which have alkoxysilyl groups and contain urethane groups, and their use EVONIK DEGUSSA GMBH (DE) 2016-05-10 US disclosed
CN-102432862-B There is the modified alkoxylated product of at least one non-end alkoxysilyl, the polymkeric substance prepared with them EVONIK DEGUSSA GMBH (DE) 2016-02-10 CN disclosed
US-9035011-B2 Modified alkoxylation products having at least one non-terminal alkoxysilyl group and a plurality of urethane groups, and their use EVONIK GOLDSCHMIDT GMBH (DE) 2015-05-19 US disclosed
CN-104418993-A Modified alkoxylation products which have alkoxysilyl groups and contain urethane groups, and their use EVONIK INDUSTRIES AG 2015-03-18 CN disclosed
US-20150057369-A1 MODIFIED ALKOXYLATION PRODUCTS WHICH HAVE ALKOXYSILYL GROUPS AND CONTAIN URETHANE GROUPS, AND THEIR USE EVONIK DEGUSSA GMBH (DE) 2015-02-26 US disclosed
EP-2840104-A1 Modified alkoxylation products containing alkoxysilyl groups and urethane groups and their use Evonik Industries AG (DE) 2015-02-25 EP disclosed
US-8883932-B2 Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK DEGUSSA GMBH (DE) 2014-11-11 US disclosed
US-20130237616-A1 MODIFIED ALKOXYLATION PRODUCTS HAVING AT LEAST ONE NON-TERMINAL ALKOXYSILYL GROUP AND A PLURALITY OF URETHANE GROUPS, AND THEIR USE EVONIK GOLDSCHMIDT GMBH (DE) 2013-09-12 US disclosed
US-20120029090-A1 Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK GOLDSCHMIDT GMBH (DE) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029090-A1 Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them TELO2, ALKBH2, SMCHD1 KDM4E 630/4885CA2 4084/4885PTGS1 2820/4885
US-20130237616-A1 MODIFIED ALKOXYLATION PRODUCTS HAVING AT LEAST ONE NON-TERMINAL ALKOXYSILYL GROUP AND A PLURALITY OF URETHANE GROUPS, AND THEIR USE ALKBH3, ALKBH2, ALKBH5 KDM4E 272/4885CA2 4355/4885PTGS1 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.