SCHEMBL451023

SCHEMBL451023

CC(=O)N[Si](C)(C)NC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
CA2 P00918 1/20 0.41
PTGS1 P23219 1/20 0.41
MMP12 P39900 1/20 0.41
NFKB1 P19838 1/20 0.39
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.33
CRBN Q96SW2 1/20 0.33
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
TAS2R38 P59533 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450522 0.79 KDM4E (0.41) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL321022 0.79
SCHEMBL27617828 0.76
SCHEMBL26965406 0.74 KDM4E (0.44) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL2987964 0.74 KDM4E (0.44) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL9721813 0.71 KDM4E (0.35) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL9065675 0.69 ALDH1A1 (0.38) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL512003 0.69 KDM4E (0.33) KDM4ECA2PTGS1MMP12NFKB1
Methylene Chloride SCHEMBL11392574 0.69 KMT2A (0.34) KDM4ECA2PTGS1MMP12NFKB1
SCHEMBL4067361 0.69 KDM4E (0.33) KDM4ECA2PTGS1MMP12NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083132-A1 THIOL-CONTAINING ALCOHOLS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME STERILE STATE, LLC (US) 2026-03-26 US claimed
EP-4622682-A1 THIOL-CONTAINING ALCOHOLS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME Sterile State LLC (US) 2025-10-01 EP claimed
WO-2024112512-A1 THIOL-CONTAINING ALCOHOLS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME STERILE STATE LLC (US) 2024-05-30 WO claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-9605113-B2 Non-metal catalyzed room temperature moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-03-28 US claimed
EP-2776162-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-01-04 EP claimed
US-9523002-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-12-20 US claimed
US-9493691-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-11-15 US claimed
WO-2016137881-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES (US) 2016-09-01 WO claimed
WO-2014163917-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-09 WO claimed
EP-2776162-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-09-17 EP claimed
EP-2614107-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2013-07-17 EP claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013090132-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013090127-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US claimed
WO-2012033886-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083132-A1 THIOL-CONTAINING ALCOHOLS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME NOS2, NOS1, NOS3 KDM4E 1794/4885CA2 3860/4885PTGS1 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.