Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823420 | 0.94 | HCRTR1 (0.40) | CCR1MEN1KMT2ACHRM4HCRTR1 | |
| SCHEMBL5123813 | 0.92 | CCR1 (0.39) | CCR1MEN1KMT2AHCRTR1 | |
| SCHEMBL5131228 | 0.92 | OPRM1 (0.47) | CCR1DRD2DRD4DRD3 | |
| SCHEMBL5122035 | 0.88 | OPRL1 (0.44) | MEN1KMT2ACHRM4HCRTR1 | |
| SCHEMBL5129990 | 0.87 | MEN1 (0.45) | MEN1KMT2AHCRTR1 | |
| SCHEMBL5132354 | 0.87 | CCR1 (0.46) | CCR1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL5128597 | 0.86 | BRD4 (0.46) | CCR1MEN1KMT2A | |
| SCHEMBL5128085 | 0.84 | PKLR (0.50) | HCRTR1 | |
| SCHEMBL3821931 | 0.82 | S1PR2 (0.43) | CCR1MEN1KMT2ACHRM4DRD2 | |
| SCHEMBL5126207 | 0.81 | OPRM1 (0.47) | CCR1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | CCR1 598/4885MEN1 1340/4885KMT2A 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.