SCHEMBL512480

SCHEMBL512480

C=C(C)C(=O)OCC1OC1C

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 4/20 0.44
THRB P10828 2/20 0.41
CYP2D6 P10635 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258768 0.85 ALDH1A1 (0.36) ALDH1A1TSHRTHRBCYP2D6HSD17B10
SCHEMBL27846329 0.83 ALDH1A1 (0.53) ALDH1A1TSHRTHRBCYP2D6CYP3A4
SCHEMBL28450769 0.81 ALDH1A1 (0.53) ALDH1A1TSHRTHRB
SCHEMBL818730 0.81 THRB (0.47) ALDH1A1TSHRTHRBPOLBAPEX1
SCHEMBL9390470 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL23199076 0.79 ALDH1A1 (0.47) ALDH1A1TSHRTHRBCYP2D6CYP3A4
SCHEMBL1499315 0.79
SCHEMBL246722 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTHRBCYP2D6CYP3A4
SCHEMBL245220 0.78 ALDH1A1 (0.50) ALDH1A1TSHRTHRB
SCHEMBL28886806 0.78 TSHR (0.51) ALDH1A1TSHRTHRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220227954-A1 POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE OAKTREE FUND ADMINISTRATION, LLC 2022-07-21 US claimed
US-20220203000-A1 MEDICAL INSTRUMENT TERUMO KABUSHIKI KAISHA (JP) 2022-06-30 US claimed
EP-3862384-A2 POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE SiO2 Medical Products, Inc. (US) 2021-08-11 EP claimed
US-7189341-B2 Transition metal catalyst, an electroconductive material such as graphite; and a polymer binder blend of high molecular weight and low molecular weight acrylic (co)polymers, one having a higher glass transition temperature (Tg); catalytic inks for screen printing; use to make electrochemical sensors ANIMAS TECHNOLOGIES, LLC (US) 2007-03-13 US claimed
EP-1211556-B1 Thermally developable imaging materials containing surface barrier layer EASTMAN KODAK CO (US) 2005-11-02 EP claimed
EP-1211556-A2 Thermally developable imaging materials containing surface barrier layer EASTMAN KODAK COMPANY (US) 2002-06-05 EP claimed
US-6350561-B1 Thermally developable imaging materials containing surface barrier layer EASTMAN KODAK COMPANY 2002-02-26 US claimed
US-5283360-A Opening epoxide ring with acidic reagent ATOCHEM (FR) 1994-02-01 US claimed
EP-0183213-B1 THERMOSETTING PREFORM HAVING SUPERIOR TRANSPARENCY AND PROCESS FOR PRODUCING MOLDED ARTICLES FROM SAID PREFORM MITSUBISHI RAYON CO., LTD. (JP) 1989-08-09 EP claimed
EP-0217660-A2 Poly (alpha hydroxy acid) copolymers A.E. STALEY MANUFACTURING COMPANY (US) 1987-04-08 EP claimed
US-4644038-A Unsaturated poly (alpha-hydroxy acid) copolymers A. E. STALEY MANUFACTURING COMPANY (US) 1987-02-17 US claimed
US-20250326908-A1 POLYMER POLYOLS, PROCESSES FOR THEIR PREPARATION, AND THE USE THEREOF TO PRODUCE POLYURETHANE FOAMS COVESTRO LLC (US) 2025-10-23 US disclosed
US-20250326907-A1 POLYMER POLYOLS, PROCESSES FOR THEIR PREPARATION, AND THE USE THEREOF TO PRODUCE POLYURETHANE FOAMS COVESTRO LLC (US) 2025-10-23 US disclosed
EP-4635998-A1 POLYMER POLYOLS, PROCESSES FOR THEIR PREPARATION, AND THE USE THEREOF TO PRODUCE POLYURETHANE FOAMS Covestro LLC (US) 2025-10-22 EP disclosed
EP-4636003-A1 POLYMER POLYOLS, PROCESSES FOR THEIR PREPARATION, AND THE USE THEREOF TO PRODUCE POLYURETHANE FOAMS Covestro LLC (US) 2025-10-22 EP disclosed
US-4452925-A Biologically stabilized compositions comprising collagen as the minor component with ethylenically unsaturated compounds used as contact lenses NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1984-06-05 US disclosed
EP-0084046-A4 HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. NAT PATENT DEV CORP (US) 1984-01-12 EP disclosed
EP-0084046-A1 HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. NAT PATENT DEV CORP (US) 1983-07-27 EP disclosed
US-4388428-A DIMENSIONALLY STABLE HYDROGEL NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1983-06-14 US disclosed
WO-1983000339-A1 HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN NAT PATENT DEV CORP (US) 1983-02-03 WO disclosed