SCHEMBL258768

SCHEMBL258768

CC1OC1COC(=O)C(=O)OCC1OC1C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.31
THRB P10828 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.30
NR3C1 P04150 1/20 0.30
FYN P06241 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADRA2B P18089 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9390470 0.89 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL512480 0.85 ALDH1A1 (0.56) ALDH1A1CYP2D6THRBHSD17B10TSHR
SCHEMBL1499315 0.83
SCHEMBL11766531 0.79 HCAR2 (0.39)
SCHEMBL11766525 0.79 HCAR2 (0.39)
SCHEMBL10071446 0.79 NAAA (0.38) ALDH1A1NR3C1FYNADRA2AADORA3
SCHEMBL10350786 0.79 HTT (0.35)
SCHEMBL1252907 0.79 PRKD3 (0.33) HSD17B10
SCHEMBL9653338 0.78 NLRP3 (0.33)
SCHEMBL259020 0.78 DGKA (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018160726-A1 LOW DIELECTRIC CONSTANT POROUS EPOXY-BASED DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2018-09-07 WO claimed
US-7517943-B2 Golf ball layer compositions formed from oxirane functional endcapped polymers ACUSHNET COMPANY (US) 2009-04-14 US claimed
US-20070129510-A1 Golf ball layer compositions formed from oxirane functional endcapped polymers ACUSHNET COMPANY 2007-06-07 US claimed
US-5552208-A High strength composite ALLIEDSIGNAL INC. (US) 1996-09-03 US claimed
US-10128890-B2 Privacy and security systems and methods of use PPIP LLC (US) 2018-11-13 US disclosed
WO-2018160726-A1 LOW DIELECTRIC CONSTANT POROUS EPOXY-BASED DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2018-09-07 WO disclosed
US-20180243967-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2018-08-30 US disclosed
US-9979427-B2 Privacy and security systems and methods of use PPIP LLC (US) 2018-05-22 US disclosed
EP-3243160-A1 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2017-11-15 EP disclosed
US-20170284773-A9 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH LTD. (US) 2017-10-05 US disclosed
US-20170234657-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2017-08-17 US disclosed
WO-2016111728-A9 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2016-10-20 WO disclosed
US-4235974-A Process for the production of epoxy cellular solid products BLOUNT DAVID H 1980-11-25 US disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed
US-4118535-A SOLVENTLESS-DRY POWDER COATINGS, FILAMENTS, FIBERS, FILMS, MOLDING COMPOUNDS GENERAL ELECTRIC COMPANY (US) 1978-10-03 US disclosed
US-4065316-A EPOXY RESIN, METHYLATED AMINO RESIN AND PIGMENT WESTERN ELECTRIC COMPANY, INCORPORATED (US) 1977-12-27 US disclosed
US-4034014-A FROM MALEIC MONOMERS AND ALKYLSTYRENES ALLIED CHEMICAL CORPORATION (US) 1977-07-05 US disclosed
US-3960813-A ADNC BLENDSADIPODI(NITRILE CARBONATE) ATLANTIC RICHFIELD COMPANY (US) 1976-06-01 US disclosed
US-3948855-A Process for reacting a phenol with a vicinal epoxy compound in the presence of phosphorus or carbon containing acid, ester or acid ester THE DOW CHEMICAL COMPANY (US) 1976-04-06 US disclosed