Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.68 |
| ▸ | ESR1 | P03372 | 3/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342317 | 0.90 | LTA4H (0.81) | LTA4HESR1ESR2MEN1KMT2A | |
| Parahydroxybenzyl Alcohol SCHEMBL62690 | 0.84 | — | — | |
| SCHEMBL12804905 | 0.83 | ESR1 (0.70) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL5488305 | 0.83 | ESR1 (0.70) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL14421265 | 0.83 | ESR1 (0.70) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL12804316 | 0.83 | ESR1 (0.70) | LTA4HESR1ESR2MEN1KMT2A | |
| Ethylene Glycol SCHEMBL3402355 | 0.82 | MEN1 (0.78) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL24780222 | 0.82 | APP (0.68) | LTA4HMEN1KMT2APARP10APP | |
| Parahydroxybenzyl Alcohol SCHEMBL10792062 | 0.82 | ESR1 (0.58) | LTA4HESR1ESR2MEN1KMT2A | |
| Parahydroxybenzyl Alcohol SCHEMBL27929616 | 0.82 | ESR1 (0.58) | LTA4HESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481965-B1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | ENDO HITOSHI (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-7345068-B2 | Aromatic amino acid derivatives and medicinal compositions | Endou, Hitoshi (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | HITOSHI ENDOU (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1481965-A1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | Endo, Hitoshi (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | SLC7A1, SLC1A5, SLC7A5 | LTA4H 2630/4885ESR1 2959/4885ESR2 2545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.