Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335768 | 0.92 | ALDH1A1 (0.51) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL30358032 | 0.92 | ALDH1A1 (0.51) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL3817730 | 0.88 | HSD17B10 (0.59) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL7286562 | 0.83 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL1760643 | 0.83 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL5567814 | 0.83 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL11048761 | 0.78 | HSD17B10 (0.64) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL28634734 | 0.76 | MTNR1A (0.44) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL4999513 | 0.76 | MTNR1A (0.44) | HSD17B10ALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL3893061 | 0.76 | IGF1R (0.46) | HSD17B10ALDH1A1TP53CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188460-A1 | Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188460-A1 | Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, BCL2, CASP3 | HSD17B10 426/4885ALDH1A1 2299/4885TP53 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.