Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129931 | 0.89 | TAS1R3 (0.46) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL403337 | 0.85 | TAOK1 (0.41) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL2258166 | 0.83 | TAS1R3 (0.46) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL400177 | 0.81 | TAS1R3 (0.50) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL402182 | 0.79 | TAS1R3 (0.48) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL401432 | 0.79 | TAS1R3 (0.48) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL436628 | 0.77 | TAOK1 (0.50) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL12361531 | 0.76 | TAS1R3 (0.44) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL1109293 | 0.75 | PPARG (0.57) | TAS1R3TAS1R1TAOK1TAOK3LMNA | |
| SCHEMBL404773 | 0.75 | PPARG (0.48) | TAS1R3TAS1R1TAOK1TAOK3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | TAS1R3 4169/4885TAS1R1 3477/4885TAOK1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.