Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131959 | 0.84 | EPHX2 (0.53) | EPHX2BDKRB1 | |
| SCHEMBL5093036 | 0.82 | ALDH1A1 (0.50) | EPHX2ALDH1A1AVPR1AAVPR1BMAPK1 | |
| SCHEMBL3808475 | 0.80 | AVPR1B (0.44) | EPHX2ALDH1A1AVPR1AAVPR1BMAPT | |
| SCHEMBL5123711 | 0.78 | EPHX2 (0.53) | EPHX2AVPR1AAVPR1BMAPK1 | |
| SCHEMBL5127113 | 0.77 | ALDH1A1 (0.43) | EPHX2ALDH1A1BDKRB1 | |
| SCHEMBL5121958 | 0.77 | BDKRB1 (0.41) | EPHX2AVPR1AAVPR1BMAPK1HSD17B10 | |
| SCHEMBL492678 | 0.76 | AVPR1A (0.43) | EPHX2ALDH1A1AVPR1AAVPR1BMAPK1 | |
| SCHEMBL4753169 | 0.76 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4E | |
| SCHEMBL493810 | 0.75 | AVPR1A (0.42) | EPHX2AVPR1AAVPR1B | |
| SCHEMBL5125598 | 0.74 | EPHX2 (0.49) | EPHX2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | EPHX2 1287/4885ALDH1A1 2737/4885AVPR1A 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.