Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132533 | 0.87 | RAB9A (0.49) | RAB9ANPC1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL1552891 | 0.80 | CHRM4 (0.49) | F10RAB9ANPC1LMNAPOLB | |
| SCHEMBL6684170 | 0.79 | EGFR (0.65) | RAB9ANPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL17866416 | 0.78 | CHRM4 (0.47) | F10RAB9ANPC1LMNAPOLB | |
| SCHEMBL1554384 | 0.72 | GRIN2B (0.71) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24007596 | 0.71 | ACVRL1 (0.59) | F10MEN1KMT2AMAPT | |
| SCHEMBL17339950 | 0.70 | RAB9A (0.66) | RAB9ANPC1LMNAALDH1A1MEN1 | |
| SCHEMBL15189660 | 0.70 | MAOB (0.69) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL1554865 | 0.69 | LTA4H (0.56) | RAB9ANPC1KDM4ELMNAPOLB | |
| SCHEMBL14638089 | 0.69 | STS (0.61) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008049000-A2 | COMBINATION THERAPY FOR PULMONARY ARTERIAL HYPERTENSION | UNITED THERAPEUTICS CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |