Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL4406239 | 0.88 | ALDH1A1 (0.44) | — | |
| Dioxane SCHEMBL35969 | 0.87 | — | — | |
| Acetonitrile SCHEMBL11848905 | 0.87 | TTR (0.50) | TTR | |
| Dioxane SCHEMBL2549097 | 0.87 | TTR (0.50) | TTR | |
| Dioxane SCHEMBL15422680 | 0.83 | TTR (0.55) | TTR | |
| Oxirane SCHEMBL6008970 | 0.83 | — | — | |
| Dioxane SCHEMBL23167502 | 0.79 | TTR (0.60) | TTR | |
| Acetonitrile SCHEMBL156477 | 0.79 | — | — | |
| Acetonitrile SCHEMBL21768801 | 0.79 | — | — | |
| Acetonitrile SCHEMBL6263408 | 0.79 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442798-B2 | Quinone-indicator antibiotics, particularly2-heptyl-3-hydroxy-4-quinolone, and analogs; regulating the expression of a bacterial gene; modulating bacteria quorum sensing signaling | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-20050009869-A1 | Novel autoinducer molecules and uses therefor | NATIONAL SCIENCE FOUNDATION | 2005-01-13 | — | — | US | disclosed |
| US-20020177715-A1 | Novel autoinducer molecules and uses therefor | UNIVERSITY OF IOWA | 2002-11-28 | — | — | US | disclosed |
| WO-2002018342-A2 | NOVEL AUTOINDUCER MOLECULES AND USES THEREFOR | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177715-A1 | Novel autoinducer molecules and uses therefor | QARS1, PGLS, SQLE | TTR 4862/4885 |
| US-20050009869-A1 | Novel autoinducer molecules and uses therefor | QARS1, PGLS, SQLE | TTR 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.