Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128723 | 0.92 | FFAR4 (0.49) | FFAR4FFAR1CTSAHSD17B1HSD17B2 | |
| SCHEMBL4430471 | 0.91 | FFAR4 (0.51) | FFAR4FFAR1CTSAHSD17B1HSD17B2 | |
| SCHEMBL5051839 | 0.90 | CTSA (0.46) | FFAR4FFAR1CTSAHSD17B1HSD17B2 | |
| SCHEMBL4441540 | 0.88 | HSD17B1 (0.51) | FFAR4FFAR1CTSAHSD17B1HSD17B2 | |
| SCHEMBL5123906 | 0.87 | FFAR1 (0.62) | FFAR4FFAR1LMNATHRATHRB | |
| SCHEMBL5126543 | 0.86 | ACACA (0.44) | FFAR4FFAR1CTSAHSD17B1HSD17B2 | |
| SCHEMBL5129447 | 0.84 | FFAR4 (0.53) | FFAR4FFAR1CHEK1CHEK2ACACB | |
| SCHEMBL5128391 | 0.83 | ROCK2 (0.45) | FFAR4FFAR1CHEK1CHEK2ACACB | |
| SCHEMBL5129232 | 0.83 | PIK3CA (0.42) | FFAR1CTSACHEK1CHEK2HSD17B1 | |
| SCHEMBL5123879 | 0.83 | FFAR1 (0.57) | FFAR4FFAR1ACACBACACALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PPARG, PPARA, PPARD | FFAR4 60/4885FFAR1 57/4885CTSA 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.