Rgi-7000

Rgi-7000

SCHEMBL512950

CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.55
SELP P16109 9/20 0.54
SELL P14151 3/20 0.52
SELE P16581 3/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CETP P11597 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22658273 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL22658269 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL22658274 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL21537086 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL24777275 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL22658272 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL24777277 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL22658271 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL23957944 1.00 APP (0.55) APPSELPSELLSELEMEN1
SCHEMBL22658268 1.00 APP (0.55) APPSELPSELLSELEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8790654-B2 Glycosylceramide adjuvant for saccharide antigens NOVARTIS AG (CH) 2014-07-29 US claimed
US-20120269832-A1 Mature Dendritic Cell Compositions and Methods of Culturing Same COIMMUNE, INC. 2012-10-25 US claimed
EP-2003969-B1 MATURE DENDRITIC CELL COMPOSITIONS AND METHODS FOR CULTURING SAME ARGOS THERAPEUTICS INC (US) 2011-05-25 EP claimed
US-7488491-B2 Use of glycosylceramides as adjuvants for vaccines against infections and cancer NEW YORK UNIVERSITY (US) 2009-02-10 US claimed
US-20080199487-A1 Glycosylceramide Adjuvant for Saccharide Antigens CHIRON SRL (IT) 2008-08-21 US claimed
US-20080145931-A1 Mature Dendritic Cell Compositions and Methods of Culturing Same ARGOS THERAPEUTICS, INC. 2008-06-19 US claimed
EP-1789059-A2 GLYCOSYLCERAMIDE ADJUVANT FOR SACCHARIDE ANTIGENS Novartis Vaccines and Diagnostics S.r.l. (IT) 2007-05-30 EP claimed
WO-2006027685-A2 GLYCOSYLCERAMIDE ADJUVANT FOR SACCHARIDE ANTIGENS NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) 2006-03-16 WO claimed
EP-1434859-A2 USE OF GLYCOSYLCERAMIDES AS ADJUVANTS FOR VACCINES AGAINST INFECTIONS AND CANCER NEW YORK UNIVERSITY (US) 2004-07-07 EP claimed
US-20030157135-A1 Use of glycosylceramides as adjuvants for vaccines against infections and cancer NEW YORK UNIVERSITY 2003-08-21 US claimed
WO-2003009812-A2 USE OF GLYCOSYLCERAMIDES AS ADJUVANTS FOR VACCINES AGAINST INFECTIONS AND CANCER NEW YORK UNIVERSITY (US) 2003-02-06 WO claimed
US-20260048115-A1 PREPARATION OF INFLUENZA VIRUS VACCINE ANTIGENS SEQIRUS UK LTD (GB) 2026-02-19 US disclosed
EP-4183412-B1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-08-14 EP disclosed
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS NOVARTIS AG (CH) 2024-07-18 US disclosed
US-11891413-B2 Vaccine against Klebsiella pneumoniae IDORSIA PHARMACEUTICALS LTD (CH) 2024-02-06 US disclosed
EP-1551228-A2 SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES New York University (US) 2005-07-13 EP disclosed
US-20040127429-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK, THE 2004-07-01 US disclosed
WO-2003105769-A2 SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 2003-12-24 WO disclosed
US-20030157135-A1 Use of glycosylceramides as adjuvants for vaccines against infections and cancer NEW YORK UNIVERSITY 2003-08-21 US disclosed
EP-1018548-A1 CELLULAR IMMUNOGENICITY POTENTIATING COMPOSITION CONTAINING $g(a)-GLYCOSYLCERAMIDE KIRIN BEER KABUSHIKI KAISHA (JP) 2000-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891413-B2 Vaccine against Klebsiella pneumoniae UBXN1, MLX, UBXN4 APP 3158/4885SELP 584/4885SELL 1510/4885
US-20080199487-A1 Glycosylceramide Adjuvant for Saccharide Antigens FUT5, SIGLEC7, FUT6 APP 2757/4885SELP 289/4885SELL 127/4885
US-20040127429-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases UGT8, UGCG, SGMS1 APP 3263/4885SELP 1036/4885SELL 2150/4885
US-20030157135-A1 Use of glycosylceramides as adjuvants for vaccines against infections and cancer UGCG, GBA1, GALC APP 2576/4885SELP 978/4885SELL 980/4885
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS FURIN, CD69, LY96 APP 400/4885SELP 486/4885SELL 621/4885
US-20260048115-A1 PREPARATION OF INFLUENZA VIRUS VACCINE ANTIGENS SIGLEC9, CD209, SIGLEC7 APP 1285/4885SELP 580/4885SELL 1488/4885
US-20120269832-A1 Mature Dendritic Cell Compositions and Methods of Culturing Same CD40, CD40LG, CCR7 APP 1368/4885SELP 1161/4885SELL 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.