Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129667 | 0.88 | ALDH1A1 (0.45) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL5129664 | 0.88 | ALDH1A1 (0.45) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL11244817 | 0.71 | ALDH1A1 (0.54) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL11553191 | 0.69 | SLC6A4 (0.54) | ALDH1A1POLBLMNARAB9AOPRD1 | |
| SCHEMBL11552626 | 0.69 | SLC6A4 (0.54) | ALDH1A1POLBLMNARAB9AOPRD1 | |
| SCHEMBL11552628 | 0.69 | SLC6A4 (0.54) | ALDH1A1POLBLMNARAB9AOPRD1 | |
| SCHEMBL12385822 | 0.66 | ALDH1A1 (0.67) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL14197774 | 0.66 | ALDH1A1 (0.67) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL2134171 | 0.65 | ALDH1A1 (1.00) | ALDH1A1POLBTACR3LMNARAB9A | |
| SCHEMBL1828872 | 0.64 | ALDH1A1 (0.68) | ALDH1A1POLBTACR3LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465751-B2 | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-16 | — | — | US | disclosed |