Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553191 | 0.83 | SLC6A4 (0.54) | ALDH1A1POLBOPRD1OPRK1SLC6A2 | |
| SCHEMBL11552626 | 0.83 | SLC6A4 (0.54) | ALDH1A1POLBOPRD1OPRK1SLC6A2 | |
| SCHEMBL11552628 | 0.83 | SLC6A4 (0.54) | ALDH1A1POLBOPRD1OPRK1SLC6A2 | |
| SCHEMBL11548123 | 0.82 | CXCR3 (0.44) | ALDH1A1POLBOPRD1OPRK1TACR3 | |
| SCHEMBL11253346 | 0.81 | SLC6A2 (0.47) | ALDH1A1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL11243848 | 0.76 | OPRM1 (0.49) | ALDH1A1POLBOPRD1OPRK1MEN1 | |
| SCHEMBL11260608 | 0.73 | OPRM1 (0.50) | OPRD1OPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11246645 | 0.73 | SLC6A4 (0.68) | OPRD1OPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11246658 | 0.73 | SLC6A4 (0.68) | OPRD1OPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12208343 | 0.73 | ALDH1A1 (0.68) | ALDH1A1POLBOPRD1OPRK1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |