Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 13/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131792 | 0.92 | HDAC1 (0.42) | HTR7BCL2BAK1DRD2CACNB4 | |
| SCHEMBL5129265 | 0.85 | BCL2 (0.45) | HTR7BCL2BAK1DRD2BCL2L1 | |
| SCHEMBL5122935 | 0.85 | HTR7 (0.40) | HTR7BCL2BAK1CACNB4CACNA1A | |
| SCHEMBL5123692 | 0.82 | DRD2 (0.51) | HTR7BCL2BAK1DRD2BCL2L1 | |
| SCHEMBL5126392 | 0.82 | DRD2 (0.51) | HTR7BCL2BAK1DRD2BCL2L1 | |
| Hydrochloric Acid SCHEMBL5132534 | 0.81 | DRD2 (0.50) | HTR7BCL2BAK1DRD2BCL2L1 | |
| SCHEMBL3822802 | 0.79 | DRD2 (0.45) | BCL2BAK1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL5123855 | 0.78 | DRD2 (0.44) | BCL2BAK1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL5128653 | 0.78 | DRD2 (0.44) | BCL2BAK1DRD2DRD4 | |
| SCHEMBL3815352 | 0.77 | DRD2 (0.42) | HTR7BCL2BAK1DRD2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188460-A1 | Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188460-A1 | Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, BCL2, CASP3 | HTR7 194/4885BCL2 2/4885BAK1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.