SCHEMBL5130232

SCHEMBL5130232

CCCCCCC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 7/20 0.73
HTR7 P34969 1/20 0.59
TP53 P04637 1/20 0.59
TSHR P16473 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
STS P08842 4/20 0.58
RARB P10826 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9626903 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9625875 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9625683 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9625687 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9626892 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9440276 1.00 HSD17B3 (0.73) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9625547 0.98 HSD17B3 (0.72) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL9346532 0.95 HSD17B3 (0.67) HSD17B3HTR7L3MBTL1MAPTRARB
SCHEMBL5456494 0.92 HSD17B3 (0.71) HSD17B3HTR7TP53TSHRL3MBTL1
SCHEMBL13085847 0.92 HSD17B3 (0.85) HSD17B3HTR7L3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
US-20080319074-A1 Glucagon Receptor Antagonists, Preparation and Therapeutic Uses ELI LILLY AND COMPANY 2008-12-25 US disclosed
EP-0304359-B1 OPTICALLY ACTIVE COMPOUND Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-05-06 EP disclosed
US-4946989-A ELECTRIC INDICATIVE ELEMENT OF LIQUID CRYSTALS SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1990-08-07 US disclosed
EP-0304359-A1 Optically active compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319074-A1 Glucagon Receptor Antagonists, Preparation and Therapeutic Uses GLP1R, GCGR, GIPR HSD17B3 803/4885HTR7 498/4885TP53 3986/4885
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SLC6A9, SLC6A5, REN HSD17B3 631/4885HTR7 4725/4885TP53 4795/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R HSD17B3 2796/4885HTR7 219/4885TP53 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.