Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130459 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAALMNACXCR2RECQL | |
| SCHEMBL5123860 | 0.85 | MAPT (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5123863 | 0.85 | MAPT (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5127407 | 0.80 | MAPT (0.36) | ALDH1A1LMNACXCR2MAPTMEN1 | |
| SCHEMBL5126008 | 0.79 | MAPT (0.51) | ALDH1A1GAACXCR2MAPTMEN1 | |
| SCHEMBL5126018 | 0.79 | MAPT (0.51) | ALDH1A1GAACXCR2MAPTMEN1 | |
| SCHEMBL5130420 | 0.76 | GSR (0.40) | ALDH1A1LMNAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL5126036 | 0.76 | GSR (0.40) | ALDH1A1LMNAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL5126033 | 0.76 | GSR (0.40) | ALDH1A1LMNAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL5122458 | 0.75 | ENPP2 (0.48) | ALDH1A1GAALMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | ALDH1A1 567/4885GAA 1175/4885LMNA 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.