Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327523 | 0.75 | HTT (0.50) | ALDH1A1KDM4EMAPTHTTHSD17B10 | |
| SCHEMBL2329963 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL243853 | 0.66 | KMT2A (0.59) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL7112477 | 0.66 | NOS2 (0.34) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL3239713 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL9322757 | 0.66 | CYP1A2 (0.42) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL13233782 | 0.65 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL4892851 | 0.64 | KDM4E (0.65) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL350783 | 0.64 | KDM4E (0.82) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL239409 | 0.64 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1715840-B1 | KERATIN DYEING COMPOSITIONS CONTAINING BICYCLIC FUSED 5-5 HETEROAROMATIC DYES | PROCTER & GAMBLE (US) | 2008-12-03 | — | — | EP | claimed |