Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323308 | 0.72 | CLK4 (0.34) | MAPTKDM4E | |
| SCHEMBL7112477 | 0.72 | NOS2 (0.34) | CYP1A2CYP2D6HTTMAPTKDM4E | |
| SCHEMBL9322770 | 0.67 | CYP1A2 (0.40) | CYP1A2CYP2D6HTTKDM4ETSHR | |
| SCHEMBL5131371 | 0.66 | ALDH1A1 (0.45) | CYP1A2CYP2D6HTTMAPTKDM4E | |
| SCHEMBL19365983 | 0.66 | KDM4E (0.43) | CYP1A2CYP2D6HTTKDM4ETSHR | |
| SCHEMBL3239713 | 0.64 | ALDH1A1 (0.41) | HTTMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL9021593 | 0.62 | POLB (0.38) | CYP1A2CYP2D6MAPTKDM4EPOLB | |
| SCHEMBL5035985 | 0.60 | HTT (0.46) | CYP1A2CYP2D6HTTMAPTKDM4E | |
| SCHEMBL5036545 | 0.60 | HTT (0.46) | CYP1A2CYP2D6HTTMAPTKDM4E | |
| SCHEMBL5037247 | 0.60 | CYP1A2 (0.46) | CYP1A2CYP2D6HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292733-A | Cephalosporin compounds | LUCKY LIMITED (KR) | 1994-03-08 | — | — | US | disclosed |
| EP-0508375-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY LTD. (KR) | 1992-10-14 | — | — | EP | disclosed |