SCHEMBL51319

SCHEMBL51319

CCc1ccc(O)c(Cc2cc(CC)ccc2O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.64
BACE1 P56817 1/20 0.55
HIF1A Q16665 3/20 0.50
MAPT P10636 2/20 0.50
HSPA5 P11021 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 2/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A1 O15245 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSPD1 P10809 1/20 0.50
IDO1 P14902 1/20 0.50
ALOX12 P18054 1/20 0.50
CASP1 P29466 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345470 0.92 AMY1A (0.56) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL1345498 0.92 AMY1A (0.56) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL1345240 0.92 AMY1A (0.56) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL1345993 0.92 AMY1A (0.56) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL1345693 0.92 AMY1A (0.56) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL9913999 0.90 CNR1 (0.58) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL1021944 0.88 BACE1 (0.68) TRPA1BACE1MAPTSMN1; SMN2ALOX15
SCHEMBL8040880 0.87 AMY1A (0.71) TRPA1BACE1HIF1AMAPTHSPA5
SCHEMBL22500692 0.87 MAPT (0.53) TRPA1BACE1MAPTMEN1CYP3A4
SCHEMBL21307639 0.86 TRPA1 (0.53) TRPA1BACE1HIF1AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040225048-A1 Vibration damping material composition TITECS JAPAN CORPORATION (JP) 2004-11-11 US claimed
EP-1408075-A1 Vibration damping material composition Titecs Japan Corporation (JP) 2004-04-14 EP claimed
EP-0633501-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-01-11 EP claimed
US-10920017-B2 Polyimide resin and resin composition KANEKA CORPORATION (JP) 2021-02-16 US disclosed
US-20190263968-A1 POLYIMIDE RESIN AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2019-08-29 US disclosed
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
EP-1724119-B1 DEVELOPER MIXTURE FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS MITSUBISHI CHEM CORP (JP) 2014-11-19 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8269358-B2 Bis(aminophenol) derivative, process for producing same, polyamide resin, positive photosensitive resin composition, protective film, interlayer dielectric film, semiconductor device, and display element SUMITOMO BAKELITE COMPANY LIMITED (JP) 2012-09-18 US disclosed
US-8202821-B2 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD (JP) 2012-06-19 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
EP-1408075-A1 Vibration damping material composition Titecs Japan Corporation (JP) 2004-04-14 EP disclosed
EP-1393923-A1 DEVELOPERS FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-03-03 EP disclosed
EP-0328364-B1 Photosensitive material CANON KK (JP) 1996-05-08 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
EP-0633501-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-01-11 EP disclosed
US-5001032-A Photosensitive material containing a photosensitive and heat developable element and a polymerizable layer and image-forming method utilizing the same CANON KABUSHIKI KAISHA (JP) 1991-03-19 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0328364-A2 Photosensitive material CANON KABUSHIKI KAISHA (JP) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 TRPA1 2233/4885BACE1 1825/4885HIF1A 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.