Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315583 | 0.89 | NPC1 (0.62) | AGTR2KMT2ANPC1AGTR1PTGDR2 | |
| SCHEMBL11747939 | 0.83 | AGTR2 (0.53) | AGTR2KMT2ANPC1AGTR1ACACB | |
| SCHEMBL3517931 | 0.81 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL8964042 | 0.81 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL16039389 | 0.79 | AGTR2 (0.52) | AGTR2AGTR1PTGDR2ACACB | |
| SCHEMBL21796225 | 0.79 | AGTR2 (0.66) | AGTR2AGTR1ACACB | |
| SCHEMBL17607347 | 0.77 | ACACB (0.49) | AGTR2KMT2ANPC1AGTR1ACACB | |
| SCHEMBL3531595 | 0.76 | AGTR2 (0.68) | AGTR2KMT2ANPC1AGTR1MEN1 | |
| SCHEMBL23315440 | 0.76 | KMT2A (0.51) | AGTR2KMT2ANPC1PTGDR2MEN1 | |
| SCHEMBL11743922 | 0.75 | AGTR2 (0.50) | AGTR2AGTR1PDE4DACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996183-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106938-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-09-27 | — | — | WO | disclosed |