Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132181 | 0.89 | AGTR2 (0.68) | NPC1KMT2AAGTR2AGTR1ACACB | |
| SCHEMBL11747939 | 0.89 | AGTR2 (0.53) | NPC1KMT2AAGTR2AGTR1ACACB | |
| SCHEMBL23315440 | 0.86 | KMT2A (0.51) | NPC1KMT2AAGTR2ACACBPTGDR2 | |
| SCHEMBL21796225 | 0.85 | AGTR2 (0.66) | AGTR2AGTR1ACACBKDM4E | |
| SCHEMBL16039389 | 0.85 | AGTR2 (0.52) | AGTR2AGTR1ACACBPTGDR2GPR183 | |
| SCHEMBL23315308 | 0.83 | KMT2A (0.51) | NPC1KMT2APTGDR2ALOX15 | |
| SCHEMBL17607347 | 0.82 | ACACB (0.49) | NPC1KMT2AAGTR2AGTR1ACACB | |
| SCHEMBL3531595 | 0.81 | AGTR2 (0.68) | NPC1KMT2AAGTR2AGTR1GPR183 | |
| SCHEMBL11743922 | 0.80 | AGTR2 (0.50) | AGTR2AGTR1ACACB | |
| SCHEMBL23315424 | 0.80 | AGTR2 (0.54) | AGTR2AGTR1ACACBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |