Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 2/20 | 0.43 |
| ▸ | ME1 | P48163 | 2/20 | 0.43 |
| ▸ | ME3 | Q16798 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315308 | 0.86 | KMT2A (0.51) | KMT2ANPC1RAB9AMEN1USP2 | |
| SCHEMBL23315583 | 0.86 | NPC1 (0.62) | KMT2ANPC1AGTR2PTGDR2GPR183 | |
| SCHEMBL17607347 | 0.78 | ACACB (0.49) | KMT2ANPC1AGTR2GPR183ACACB | |
| SCHEMBL23315634 | 0.77 | AGTR2 (0.73) | AGTR2 | |
| SCHEMBL23315251 | 0.77 | AGTR2 (0.51) | AGTR2ACACB | |
| SCHEMBL5132181 | 0.76 | AGTR2 (0.68) | KMT2ANPC1AGTR2MEN1PTGDR2 | |
| SCHEMBL11747939 | 0.74 | AGTR2 (0.53) | KMT2ANPC1AGTR2GPR183ACACB | |
| SCHEMBL29569463 | 0.73 | NPC1 (0.78) | KMT2ANPC1RAB9AMEN1TSHR | |
| SCHEMBL25605335 | 0.73 | NPC1 (0.78) | KMT2ANPC1RAB9AMEN1TSHR | |
| SCHEMBL17583938 | 0.72 | ESR2 (0.50) | AGTR2PTGDR2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |