Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943110 | 0.70 | GSK3A (0.46) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL7338785 | 0.69 | GSK3A (0.43) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL6829797 | 0.68 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL29697065 | 0.68 | CRBN (0.38) | HPGDHTTMEN1ALDH1A1POLB | |
| SCHEMBL9527717 | 0.66 | GSK3A (0.46) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL5132370 | 0.65 | HPGD (0.36) | HPGDHTTMEN1ALDH1A1POLB | |
| SCHEMBL4725102 | 0.63 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL6479874 | 0.62 | ALDH1A1 (0.36) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL7627774 | 0.62 | ALDH1A1 (0.36) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL3672037 | 0.59 | CRBN (0.44) | GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037792-A2 | BENZO (F) QUINOLINONE VARIANTS AS NUCLEAR HORMONE RECEPTOR LIGANDS | KARO BIO AB (SE) | 2004-05-06 | — | — | WO | disclosed |