SCHEMBL8014236

SCHEMBL8014236

O=C1NC(=O)C(=C2CCCC2)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
BLM P54132 3/20 0.41
RECQL P46063 2/20 0.41
KDM4E B2RXH2 1/20 0.41
OGT O15294 1/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 3/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
PLCG1 P19174 1/20 0.39
APEX1 P27695 1/20 0.39
APOBEC3A P31941 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ESR2 Q92731 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8024783 0.80 HPGD (0.45) MAPTBLMRECQLHPGDHTT
SCHEMBL123424 0.65
SCHEMBL14964727 0.61 TDP2 (0.38) HPGDALDH1A1HSD17B10CRBN
Alloxan SCHEMBL64547 0.60 MAPT (1.00) MAPTBLMRECQLKDM4EOGT
SCHEMBL171230 0.59 CRBN (0.40) MAPTBLMRECQLHPGDHTT
SCHEMBL21312914 0.59 CRBN (0.75) MAPTBLMRECQLKDM4EOGT
SCHEMBL10618947 0.59 CRBN (0.37) CRBN
SCHEMBL2762093 0.57 ALDH1A1 (0.42) MAPTBLMRECQLHPGDHTT
SCHEMBL502060 0.57 ALDH1A1 (0.42) MAPTBLMRECQLHPGDHTT
SCHEMBL8997536 0.57 KDM4E (0.56) MAPTBLMRECQLKDM4EOGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6153356-A MIXTURE OF UNSATURATED COMPOUND, CYANINE DYE AND PHOTOINITIATOR MITSUBISHI CHEMICAL CORPORATION (JP) 2000-11-28 US disclosed