Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126232 | 0.94 | ALDH1A1 (0.49) | ALDH1A1PLA2G4BTHRATHRBLMNA | |
| SCHEMBL5131736 | 0.92 | ALDH1A1 (0.51) | ALDH1A1PLA2G4BTHRATHRBLMNA | |
| SCHEMBL5131799 | 0.92 | MMP2 (0.48) | ALDH1A1LMNAL3MBTL1CA12CA1 | |
| SCHEMBL5051566 | 0.92 | MMP2 (0.48) | ALDH1A1PLA2G4BTHRATHRBLMNA | |
| SCHEMBL5132171 | 0.91 | PLA2G4B (0.50) | ALDH1A1PLA2G4BTHRATHRBLMNA | |
| SCHEMBL5131739 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PLA2G4BLMNAL3MBTL1CA12 | |
| SCHEMBL5132331 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PLA2G4BLMNAL3MBTL1CA12 | |
| SCHEMBL5132532 | 0.89 | KAT6A (0.43) | ALDH1A1PLA2G4BTHRATHRBLMNA | |
| SCHEMBL5132239 | 0.89 | ALDH1A1 (0.44) | ALDH1A1PLA2G4BLMNAL3MBTL1CA12 | |
| SCHEMBL14605697 | 0.89 | LTA4H (0.50) | ALDH1A1PLA2G4BTHRATHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PPARG, PPARA, PPARD | ALDH1A1 789/4885PLA2G4B 664/4885THRA 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.