Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604420 | 0.78 | CACNA1H (0.39) | CNR2ARCACNA1HMEN1ALDH1A1 | |
| SCHEMBL1104684 | 0.77 | KIF11 (0.42) | ARCACNA1HMEN1ALDH1A1POLB | |
| SCHEMBL600985 | 0.77 | CACNA1H (0.39) | CNR2ARCACNA1HMEN1ALDH1A1 | |
| SCHEMBL23683520 | 0.74 | TRPV4 (0.41) | CNR2ARCACNA1HGRM4NR3C1 | |
| SCHEMBL10276227 | 0.74 | CACNA1H (0.39) | CNR2ARCACNA1HMEN1ALDH1A1 | |
| SCHEMBL2989857 | 0.74 | TRPA1 (0.41) | CNR2ARCACNA1HMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL602784 | 0.72 | CACNA1H (0.39) | CNR2ARCACNA1HMEN1ALDH1A1 | |
| SCHEMBL13259021 | 0.72 | AR (0.43) | CNR2ARCACNA1HAKR1C3AKR1C2 | |
| SCHEMBL7037031 | 0.71 | MEN1 (0.46) | MEN1MAPTKMT2ASMN1; SMN2SLC22A12 | |
| SCHEMBL283060 | 0.71 | TRPV4 (0.45) | ARPTGDR2NR3C1PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183289-B2 | 4-substituted phenoxyphenylacetic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2012-05-22 | — | — | US | disclosed |