Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 7/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558033 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL27632604 | 0.95 | NOS3 (0.46) | NOS3NOS1NOS2NUDT1GRM4 | |
| Hydrochloric Acid SCHEMBL28160401 | 0.95 | NOS3 (0.46) | NOS3NOS1NOS2NUDT1GRM4 | |
| SCHEMBL31656490 | 0.82 | — | — | |
| SCHEMBL879562 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29151203 | 0.80 | NUDT1 (0.46) | NOS3NOS1NOS2NUDT1GRM4 | |
| SCHEMBL3655582 | 0.78 | — | — | |
| SCHEMBL19313257 | 0.77 | — | — | |
| SCHEMBL13328697 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL15795891 | 0.74 | NOS3 (0.39) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | claimed |
| CN-103827665-A | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2014-05-28 | — | — | CN | disclosed |