SCHEMBL5133396

SCHEMBL5133396

ClC1c2ccccc2Sc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.41
HTR2C P28335 5/20 0.39
HRH1 P35367 5/20 0.39
CYP2D6 P10635 3/20 0.39
SLC6A2 P23975 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 2/20 0.39
NOX1 Q9Y5S8 2/20 0.39
BCHE P06276 2/20 0.39
HTR2A P28223 2/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866375 0.84 MAOA (0.31) MAOAMAPTALOX12TDP1
SCHEMBL11704742 0.80 MAOA (0.34) MAOAHTR2CHRH1CYP2D6SLC6A2
SCHEMBL4708551 0.80 S100A4 (0.42) CYP2D6SLC6A2CYP1A2CYP3A4MEN1
SCHEMBL904813 0.79 MAOA (0.41) MAOAHTR2CHRH1CYP2D6SLC6A2
SCHEMBL4707146 0.75 MEN1 (0.35) HTR2CHRH1CYP2D6SLC6A2TP53
SCHEMBL4707143 0.75 MEN1 (0.35) HTR2CHRH1CYP2D6SLC6A2TP53
SCHEMBL3068122 0.75 MAOA (0.38) MAOAHTR2CHRH1CYP2D6SLC6A2
SCHEMBL16835553 0.74 HTR2C (0.46) MAOAHTR2CHRH1CYP2D6SLC6A2
SCHEMBL7400164 0.74 HTR2C (0.39) MAOAHTR2CHRH1CYP2D6SLC6A2
SCHEMBL29697456 0.74 MAOA (0.46) MAOAHTR2CHRH1CYP2D6SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776014-A Tobacco continuous cropping soil regulator and preparation method thereof 台沃科技集团股份有限公司 2025-04-08 CN claimed
CN-119776014-A Tobacco continuous cropping soil regulator and preparation method thereof 台沃科技集团股份有限公司 2025-04-08 CN disclosed
CN-119184079-A Microcapsule structure agrochemical based on protein amyloid aggregates 陕西师范大学 2024-12-27 CN disclosed
US-20240101999-A1 HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS THERMO FISHER SCIENTIFIC GENEART GMBH (DE) 2024-03-28 US disclosed
CN-115927293-A Efficient small volume nucleic acid synthesis 生命技术公司 2023-04-07 CN disclosed
CN-107532129-B Efficient small volume nucleic acid synthesis 生命技术公司 2022-09-13 CN disclosed
CN-112040958-A Peptide-containing formulations 科巴公司 2020-12-04 CN disclosed
EP-3557262-A1 HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS Life Technologies Corporation (US) 2019-10-23 EP disclosed
US-10407676-B2 High efficiency, small volume nucleic acid synthesis Life Technologies Corporation (US) 2019-09-10 US disclosed
EP-3229959-B1 HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS LIFE TECHNOLOGIES CORP (US) 2019-05-15 EP disclosed
WO-2016094512-A1 HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS yLIFE TECHNOLOGIES CORPORATION (US) 2016-06-16 WO disclosed
EP-1996947-A1 METHOD FOR FORMING MOLECULAR SEQUENCES ON SURFACES The Regents of the University of Michigan (US) 2008-12-03 EP disclosed
WO-2008118167-A1 METHOD FOR FORMING MOLECULAR SEQUENCES ON SURFACES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2008-10-02 WO disclosed
US-20070224616-A1 METHOD FOR FORMING MOLECULAR SEQUENCES ON SURFACES NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-09-27 US disclosed
EP-1170324-B1 SHEET-FORM PHOTOCURABLE MATERIAL DAINIPPON INK & CHEMICALS (JP) 2006-03-08 EP disclosed
US-6974784-B1 Sheet-form photocurable material DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-12-13 US disclosed
US-6596456-B2 High photospeed and resolution, ensure a high durability on the press and also a low tendency to form sludge in the developing processor during developing and which do not require developers with a high content of organic solvents KODAK POLYCHROME GRAPHICS LLC 2003-07-22 US disclosed
US-20030091925-A1 Use of cinnamic acid groups containing acetal polymers for radiation-sensitive compositions and lithographic printing plates QUALEX INC. 2003-05-15 US disclosed
WO-2002096961-A1 USE OF CINNAMIC ACID GROUPS CONTAINING ACETAL POLYMERS FOR RADIATION-SENSITIVE COMPOSITIONS AND LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2002-12-05 WO disclosed
EP-1170324-A1 SHEET-FORM PHOTOCURABLE MATERIAL DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-01-09 EP disclosed