Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518141 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1GAAMEN1CXCR2 | |
| SCHEMBL2488220 | 0.83 | KMT2A (0.58) | KMT2AALDH1A1GAAMEN1PTGS1 | |
| SCHEMBL2485143 | 0.83 | KMT2A (0.58) | KMT2AALDH1A1GAAMEN1PTGS1 | |
| SCHEMBL12022633 | 0.83 | CXCR2 (0.42) | KMT2AALDH1A1GAAMEN1CXCR2 | |
| SCHEMBL28690906 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1GAAMEN1CXCR2 | |
| SCHEMBL29524587 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1GAAMEN1CXCR2 | |
| SCHEMBL27627675 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1GAAMEN1KDM4E | |
| SCHEMBL2961457 | 0.81 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1CXCR2LMNA | |
| SCHEMBL5133280 | 0.80 | CA12 (0.44) | KMT2AALDH1A1MEN1LMNAL3MBTL1 | |
| SCHEMBL5555255 | 0.80 | CA12 (0.44) | KMT2AALDH1A1MEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940767-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007030567-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |