Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591292 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAACYP3A4LMNA | |
| SCHEMBL7701652 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1GAAKLK7CYP3A4 | |
| SCHEMBL7701655 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1GAAKLK7CYP3A4 | |
| SCHEMBL27941972 | 0.81 | LMNA (0.43) | KMT2AALDH1A1GAACYP3A4LMNA | |
| SCHEMBL27518141 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL5133472 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL5892872 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1GAACYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL27923208 | 0.80 | LMNA (0.42) | KMT2AALDH1A1GAACYP3A4LMNA | |
| SCHEMBL7512529 | 0.80 | ALDH1A1 (0.64) | KMT2AALDH1A1GAAKLK7CYP3A4 | |
| SCHEMBL8997426 | 0.80 | ALDH1A1 (0.64) | KMT2AALDH1A1GAAKLK7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1700911-A | Combination drug | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |