Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 7/20 | 0.45 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084198 | 0.81 | CYP3A4 (0.47) | HPGDTK1UPP1 | |
| SCHEMBL13723199 | 0.76 | TYMP (0.45) | HPGDTK1TK2MAPK1 | |
| SCHEMBL6722443 | 0.75 | HPGD (0.68) | HPGDTK1UPP1TK2MAPK1 | |
| SCHEMBL13724173 | 0.74 | MEN1 (0.55) | HPGDTK1TK2MAPK1 | |
| SCHEMBL4094755 | 0.74 | TK1 (0.63) | HPGDTK1UPP1TK2MAPK1 | |
| SCHEMBL5065503 | 0.73 | EGFR (0.46) | HPGDMAPK1 | |
| SCHEMBL13749275 | 0.73 | TYMP (0.42) | HPGDTK1MAPK1 | |
| Hydrochloric Acid SCHEMBL4094750 | 0.73 | MAPK1 (0.55) | HPGDTK1TK2MAPK1 | |
| SCHEMBL8444516 | 0.71 | TYMP (0.49) | HPGDTK1TK2MAPK1 | |
| SCHEMBL21522987 | 0.71 | HPGD (0.62) | HPGDTK1TK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001488-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | Alt Solutions, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007106561-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | ALT SOLUTIONS, INC. (US) | 2007-09-20 | — | — | WO | disclosed |