Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780707 | 0.87 | TYMP (0.61) | TYMPKMT2AMAPK1TK1HPGD | |
| SCHEMBL23897613 | 0.86 | MAPK1 (0.51) | TYMPMAPK1TK1HPGD | |
| SCHEMBL13671535 | 0.84 | GRIA1 (0.47) | MEN1TSHRKMT2A | |
| SCHEMBL11099078 | 0.84 | LMNA (0.51) | MEN1TSHRKMT2A | |
| SCHEMBL13723199 | 0.84 | TYMP (0.45) | TYMPMEN1KMT2AMAPK1TK1 | |
| SCHEMBL4088248 | 0.82 | UPP1 (0.57) | TYMPMAPK1HPGD | |
| SCHEMBL13402919 | 0.82 | TYMP (0.54) | TYMPMAPK1TK1HPGDTK2 | |
| SCHEMBL13724173 | 0.82 | MEN1 (0.55) | TYMPMEN1KMT2AMAPK1TK1 | |
| SCHEMBL4094755 | 0.82 | TK1 (0.63) | MAPK1TK1HPGDTK2 | |
| SCHEMBL10457105 | 0.81 | KMT2A (0.43) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9124612-A | — | — | None | — | — | JP | disclosed |
| EP-0766691-B1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX INC (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5679684-A | INTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS, NERVOUS SYSTEM DISORDERS, AIDS | MACRONEX, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| JP-H09124612-A | PRODUCTION OF ACYCLONUCLEOSIDE | MITSUBISHI CHEM CORP | 1997-05-13 | — | — | JP | disclosed |
| EP-0766691-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| US-5550132-A | TREATING SEPTIC SHOCK, CACHEXIA, RHEUMATOID ARTHRITIS, INFLAMMATORY BOWEL DISEASE, MULTIPLE SCLEROSIS, AIDS | UNIVERSITY OF NORTH CAROLINA (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1995035304-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1995-12-28 | — | — | WO | disclosed |